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Unravelling the mystery of infant B-ALL: researchers uncover novel tumor biology clues

Written by Jade Parker, Senior Editor

B-ALL infants

A multi-institutional team of researchers have studied the cell biology of B-acute lymphoblastic leukemia (B-ALL) in young children and uncovered new potential drug targets for this difficult-to-treat cancer. B-ALL is caused by a malfunction in the cell development of B-lymphocytes. The disease was once a universally fatal disease in children, but treatment success rates have increased and it is now curable for the majority of patients. However, there is still a lag in successful treatment outcomes for B-ALL in infants below one year of age. In this study, the researchers studied KMT2A-rearranged infant B-ALL and discovered that these infant B-ALL...

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